Evidence supporting the use of: Lactobacillus johnsonii
For the health condition: Lactose Intolerance

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus johnsonii has been investigated for its potential to support lactose intolerance due to its ability to produce the enzyme β-galactosidase (lactase), which helps break down lactose in the gut. Several animal and small human studies have suggested that supplementation with certain strains of L. johnsonii can improve lactose digestion and reduce symptoms associated with lactose intolerance, such as bloating, gas, and diarrhea. For example, some clinical trials have shown that fermented dairy products containing L. johnsonii can reduce breath hydrogen excretion (a marker of lactose maldigestion) and improve gastrointestinal comfort in lactose-intolerant individuals. However, the overall body of evidence is limited; most studies have small sample sizes, and there is variability in the strains used and outcomes measured. Reviews of probiotic use for lactose intolerance frequently mention L. johnsonii as a promising candidate, but emphasize that more large-scale, high-quality randomized controlled trials are needed to confirm efficacy and determine optimal dosing. Thus, while the use of L. johnsonii for lactose intolerance is scientifically plausible and supported by preliminary data, the evidence base is not yet strong or definitive.

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