Evidence supporting the use of: Lactobacillus (mixed)
For the health condition: Lactose Intolerance

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

There is some scientific evidence supporting the use of mixed Lactobacillus species for the management of lactose intolerance. Lactose intolerance results from reduced activity of the enzyme lactase in the small intestine, leading to gastrointestinal symptoms when lactose-containing foods are consumed. Certain strains of Lactobacillus possess β-galactosidase (lactase) activity, which can help break down lactose in the gut. Clinical studies have shown that probiotic preparations containing Lactobacillus acidophilus, Lactobacillus bulgaricus, and other related species can alleviate symptoms (such as bloating, flatulence, and diarrhea) in lactose-intolerant individuals, particularly when consumed regularly.

The mechanism involves these bacteria surviving transit through the gastrointestinal tract and assisting in lactose digestion either by directly hydrolyzing lactose in the gut or by improving the gut microbiota composition. Yogurt containing live cultures is a classic example, as it is often better tolerated than milk by lactose-intolerant individuals due to bacterial lactase activity. Nevertheless, the magnitude of benefit can vary depending on the specific strains used, their viability, dosage, and individual differences among patients. Systematic reviews and meta-analyses conclude that while there is moderate evidence for symptom improvement, results are not universally consistent, and not all products are equally effective. Thus, while not a cure, Lactobacillus probiotics represent a scientifically plausible adjunct for managing lactose intolerance.

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