Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Senna, derived from the leaves and pods of the Senna alexandrina plant, has a long history of use as a natural laxative for supporting the function of the large intestine (colon). Its primary active compounds, senna glycosides (sennosides), are well-studied for their stimulant laxative effects. Upon ingestion, sennosides are metabolized by gut bacteria in the colon to produce active metabolites that stimulate peristalsis (the muscular contractions that move stool through the colon) and alter electrolyte transport, resulting in increased water secretion into the colon and promoting bowel movements.

The use of senna as a laxative is supported by both traditional use in herbal medicine and by strong scientific evidence. Numerous clinical trials and systematic reviews (such as those in the Cochrane Library) confirm that senna is effective in treating short-term constipation in adults and children. Senna is commonly recommended for bowel preparation before colonoscopy and is an over-the-counter remedy in many countries. However, its use is not recommended for chronic constipation or long-term use due to the risk of electrolyte imbalance, dependency, and potential damage to the colonic mucosa.

In summary, the use of senna to support the large intestine is validated by scientific research, with substantial clinical evidence demonstrating its efficacy as a short-term stimulant laxative. Its mechanism of action, efficacy, and safety profile (when used appropriately) are well-documented in the medical literature.

More about Senna (unspecified)
More about Large Intestines (Colon)

Other ingredients that support Large Intestines (Colon)

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akkermansia muciniphila
allspice
aloe vera
alpha-galactosidase
anthocyanins
apple
arabinogalactan
bacillus clausii
bacillus coagulans
bacillus subtilis
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bifidobacterium bifidum
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bifidobacterium infantis
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black garlic
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chia seed
chicory
chloride
chlorophyll
cinnamon
citrus pectin
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collard
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curcumin
d-glucarate
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guar gum
cellulose
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inulin
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lactobacillus brevis
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lactobacillus jensenii
lactobacillus paracasei
lactiplantibacillus plantarum
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lactobacillus salivarius
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lemon
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Other body systems supported by Senna (unspecified)

Digestive System
Gastrointestinal Tract
Intestinal System
Large Intestines (Colon)
Rectum

Products containing Senna (unspecified)

We currently have no products on Vitabase that contain this ingredient.