Evidence supporting the use of: Vasicine
For the health condition: Laryngitis
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Vasicine is an alkaloid derived from the plant Adhatoda vasica (commonly known as Malabar nut or Vasaka). Its use in treating or supporting laryngitis is primarily rooted in traditional medicine, particularly within Ayurveda and Unani systems. Historically, extracts of Adhatoda vasica have been employed to relieve symptoms of respiratory ailments such as cough, bronchitis, asthma, and throat inflammation, which can overlap with symptoms of laryngitis. The plant is valued for its expectorant, bronchodilator, and anti-inflammatory properties, largely attributed to vasicine.
While there are some preclinical and animal studies that demonstrate anti-inflammatory and bronchodilatory effects of vasicine, direct scientific studies specifically investigating its efficacy in laryngitis (inflammation of the larynx) are lacking. Most available evidence comprises traditional use and reports of symptomatic relief in broader respiratory conditions. There is a paucity of well-designed clinical trials in humans evaluating vasicine or Adhatoda vasica extracts specifically for laryngitis. Therefore, the use of vasicine for laryngitis is justified mainly by traditional practices, with modest scientific rationale based on its general effects on airway inflammation and mucus clearance, but no direct clinical validation for this particular indication.
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