Evidence supporting the use of: Bifidobacterium
For the health condition: Leaky Gut Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bifidobacterium species are commonly included in probiotic formulations and have been studied for their effects on gut barrier function. "Leaky Gut Syndrome" is a non-medical term generally referring to increased intestinal permeability, which is implicated in various gastrointestinal disorders. Several preclinical (animal and in vitro) studies suggest that certain strains of Bifidobacterium can enhance the integrity of the intestinal barrier by increasing the expression of tight junction proteins and reducing inflammation. Some small human studies have shown that probiotics containing Bifidobacterium can decrease intestinal permeability in specific conditions, such as irritable bowel syndrome or after NSAID use. However, the evidence in humans is limited, heterogeneous, and often involves multi-strain probiotics, making it difficult to isolate the effect of Bifidobacterium alone or to generalize to all populations.

There is no robust, large-scale clinical evidence specifically supporting the use of Bifidobacterium (unspecified) for the treatment of "Leaky Gut Syndrome" as a formal diagnosis, largely because the syndrome itself is not universally recognized in conventional medicine. Nonetheless, the available preliminary research provides a modest scientific rationale for their potential role in supporting gut barrier function, justifying a rating of 2/5 for evidence.

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Products containing Bifidobacterium

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