Evidence supporting the use of: Bifobacterium (mixed)
For the health condition: Leaky Gut Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bifidobacterium (mixed strains) are commonly included in probiotic supplements aimed at improving gut health, including conditions described as "Leaky Gut Syndrome" (increased intestinal permeability). Scientific studies, primarily in vitro and animal models, show that certain Bifidobacterium strains can enhance intestinal barrier function by increasing the expression of tight junction proteins and reducing inflammation. Some small human studies have indicated that probiotics containing Bifidobacterium may reduce gut permeability in specific populations, such as patients with irritable bowel syndrome or those under stress. However, direct evidence for their effectiveness in treating "Leaky Gut Syndrome" as a clinical entity is limited, partly because "Leaky Gut Syndrome" is not universally recognized as a formal medical diagnosis. Most available clinical trials focus on related conditions (such as IBS, IBD, or antibiotic-associated diarrhea) rather than leaky gut per se. The overall quality of evidence is moderate at best, with few high-quality randomized controlled trials specifically targeting intestinal permeability in otherwise healthy adults. Thus, while there is a plausible mechanism and some supportive data, the evidence is not robust or specific enough to warrant a higher confidence rating.

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Products containing Bifobacterium (mixed)

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