Evidence supporting the use of: Lactococcus rhamnosus
For the health condition: Leaky Gut Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactococcus rhamnosus is a probiotic bacterium often discussed in relation to gut health, including conditions described as "Leaky Gut Syndrome" (increased intestinal permeability). The use of this probiotic for leaky gut has some scientific basis, though the evidence remains limited and primarily preclinical or indirect.

Research indicates that certain strains, especially Lactobacillus rhamnosus GG (often now classified as Lactococcus or Lacticaseibacillus rhamnosus GG), can enhance intestinal barrier function. Preclinical studies in animal models have shown that supplementation with L. rhamnosus can increase the production of tight junction proteins, thereby reducing permeability and inflammation. Some human studies have indicated benefits in related conditions, such as irritable bowel syndrome or antibiotic-associated diarrhea, suggesting a general supportive effect on gut health.

However, direct evidence from human clinical trials specifically targeting "Leaky Gut Syndrome" as a defined clinical entity is sparse. The syndrome itself is not universally recognized as a formal medical diagnosis, and most studies focus on gut permeability in the context of other diseases. As such, while there is a plausible mechanism and some supportive data, the evidence is not robust or conclusive.

Overall, the use of Lactococcus rhamnosus for leaky gut is scientifically motivated but supported by low to moderate quality evidence, warranting a cautious approach.

More about Lactococcus rhamnosus
More about Leaky Gut Syndrome

Products containing Lactococcus rhamnosus

We currently have no products on Vitabase that contain this ingredient.