Evidence supporting the use of: Probiotics
For the health condition: Leaky Gut Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Probiotics are live microorganisms that are commonly used to support gut health and have been investigated for their potential role in managing "Leaky Gut Syndrome"—a condition characterized by increased intestinal permeability. The rationale for probiotic use in this context is based on their ability to modulate the gut microbiota, enhance the intestinal barrier, and reduce inflammation. Several animal and in vitro studies suggest that specific probiotic strains, such as Lactobacillus and Bifidobacterium, can improve tight junction integrity and decrease gut permeability. Some small clinical studies in humans with related conditions (e.g., irritable bowel syndrome, inflammatory bowel disease) report improvements in markers of gut barrier function following probiotic supplementation. However, direct high-quality clinical evidence for probiotics specifically treating "Leaky Gut Syndrome" in humans remains limited and inconsistent. The condition itself is not universally recognized as a distinct medical diagnosis, which complicates research and interpretation of results. Overall, while there is a plausible scientific basis and some preliminary evidence supporting the use of probiotics to support gut barrier function, robust clinical trials are lacking. The evidence is therefore moderate to low (rated 2 out of 5), and more research is needed to clarify which strains, doses, and patient populations may benefit.

More about probiotics
More about Leaky Gut Syndrome

Products containing probiotics

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