Evidence supporting the use of: Alsonia scholaris
For the health condition: Leprosy

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Alstonia scholaris has a long history of use in traditional medicine systems, particularly Ayurveda and folk medicine in India and Southeast Asia, for the management of various chronic skin diseases, including leprosy (Hansen’s disease). The bark, commonly referred to as “Saptaparna,” is described in classical Ayurvedic texts as being beneficial for skin disorders (“Kushta”), a category that historically encompassed leprosy. Traditional uses typically involve decoctions or powders of the bark as part of multi-herb formulations.

However, the scientific evidence supporting its efficacy specifically for leprosy is limited. Some pharmacological studies have demonstrated that extracts of Alstonia scholaris possess anti-inflammatory, immunomodulatory, and antimicrobial properties, which are theoretically relevant to the management of infectious and inflammatory skin conditions. Nonetheless, there are no robust clinical trials or in vivo studies directly assessing its effect on Mycobacterium leprae or on patients with leprosy. Most references to its use for leprosy are found in ethnobotanical surveys and compilations of traditional knowledge.

In summary, the use of Alstonia scholaris for leprosy is rooted in traditional practice and historical texts, with limited contemporary scientific validation for this specific indication. The evidence is largely anecdotal and traditional, warranting a low evidence score.

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