Evidence supporting the use of: Aloe
For the health condition: Lesions

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Aloe vera has a long history of traditional use for treating skin lesions, wounds, and burns, and its topical application is now supported by a growing body of scientific evidence. Several in vitro, animal, and human studies have demonstrated that Aloe vera gel possesses properties that may enhance wound healing, reduce inflammation, and promote tissue regeneration. Key bioactive compounds in Aloe vera—such as polysaccharides (notably acemannan), glycoproteins, and vitamins—are believed to contribute to these effects by stimulating fibroblast activity, collagen synthesis, and angiogenesis, and by providing antimicrobial action.

Clinical trials have investigated Aloe vera gel in the management of various lesions, including minor burns, surgical wounds, and pressure ulcers. Some studies report faster healing times, reduced pain, and better cosmetic outcomes when Aloe is used as an adjunct to standard wound care. However, results are mixed, with other trials failing to show significant benefits over placebo or conventional treatments. Systematic reviews and meta-analyses generally conclude that Aloe vera may provide some benefit for superficial lesions, particularly minor burns, but that more high-quality, well-controlled studies are needed to confirm its efficacy and determine optimal formulations and dosing.

In summary, Aloe vera is widely used and accepted for lesion care, with moderate scientific evidence supporting its topical application, especially for minor skin injuries. Its use is safe for most people, though allergic reactions are possible. The evidence base is strongest for superficial wounds and burns, while benefits for more severe or chronic lesions remain less well established.

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