Jojoba oil has been traditionally used for various skin ailments, including lesions such as minor wounds, cuts, and abrasions. Its use is rooted in indigenous practices, particularly among Native American tribes, who applied jojoba oil to the skin for its soothing and protective properties. The rationale for applying jojoba oil to lesions lies in its moisturizing effects and its similarity to human sebum, which theoretically helps maintain skin barrier function and prevent dryness. Furthermore, jojoba oil contains naturally occurring compounds like vitamin E and fatty acids, which are believed to promote skin healing and reduce inflammation in traditional medicine systems.

However, the scientific evidence supporting the use of jojoba oil specifically for treating lesions is limited. While in vitro studies have demonstrated that jojoba oil may have anti-inflammatory and mild antimicrobial properties, there is a lack of robust clinical trials evaluating its effectiveness for treating or accelerating the healing of skin lesions in humans. Most of the available evidence is anecdotal or based on traditional use rather than rigorous scientific validation. Thus, while jojoba oil is widely used in skincare for its emollient properties, its effectiveness for lesions should be considered primarily traditional, with only modest supporting evidence.