Evidence supporting the use of: Almond mushroom
For the health condition: Leukemia

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The use of the almond mushroom (Agaricus blazei Murill, also known as Himematsutake or "almond mushroom") to support or treat leukemia is rooted primarily in traditional and folk medicine, particularly in Japan and Brazil. Historically, this mushroom has been consumed for its purported health benefits, including immune modulation and cancer support. Anecdotal reports and traditional practices have suggested its use as an adjunct therapy in various cancers, including leukemia, due to its high content of polysaccharides (notably beta-glucans), which are believed to enhance immune function.

Scientific studies investigating the direct effects of Agaricus blazei on leukemia are limited and mostly preclinical. Some in vitro and animal studies have shown immunomodulatory and potential anti-tumor activities, such as enhanced activity of natural killer cells and macrophages, and induction of apoptosis in certain cancer cell lines. However, robust clinical trials in humans with leukemia are lacking. The available evidence is insufficient to conclusively validate its efficacy or safety as a leukemia treatment. As such, while its traditional use for general cancer support is documented, scientific validation remains preliminary, and the current evidence level supporting its use in leukemia specifically is low.

Patients considering Agaricus blazei should consult healthcare professionals, especially as it is not a substitute for standard leukemia therapies. Potential interactions and side effects must also be considered.

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