Evidence supporting the use of: Streptomyces (unspecified)
For the health condition: Lice

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Streptomyces species are scientifically significant in the treatment of lice due to their role in the production of certain antiparasitic compounds. The most notable example is Streptomyces avermitilis, which produces avermectins, a group of macrocyclic lactones. Ivermectin, a semi-synthetic derivative of avermectin, has been widely used as an oral and topical agent for treating head lice (Pediculus humanus capitis) infestations. Multiple randomized controlled trials and systematic reviews have demonstrated the efficacy of ivermectin against lice, especially in cases resistant to traditional insecticidal treatments such as permethrin or pyrethrins.

The use of Streptomyces-derived compounds is thus firmly grounded in scientific evidence, with their mechanism of action involving interference with neurotransmission in the parasite, leading to paralysis and death of the lice. The World Health Organization and the Centers for Disease Control and Prevention recognize ivermectin as a treatment option for lice. However, it is important to note that while it is the compounds produced by Streptomyces that are used (not the organism itself), their discovery and development represent a clear case of scientific validation for the use of Streptomyces derivatives in lice treatment.

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