Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to reduce pain and inflammation associated with musculoskeletal injuries, including those involving ligaments such as sprains and partial tears. The scientific rationale for its use lies in its ability to inhibit cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of inflammation and pain. Clinical guidelines and studies support the use of NSAIDs like diclofenac for short-term management of pain and swelling following ligament injuries, particularly in acute settings. For example, topical and oral diclofenac have been shown to provide symptomatic relief in soft tissue injuries, which include ligament sprains, according to systematic reviews and randomized controlled trials. However, there is no evidence that diclofenac accelerates the biological healing of torn ligaments; rather, it serves to manage symptoms such as pain and inflammation while the body undergoes natural repair processes. Prolonged or excessive use of NSAIDs may potentially interfere with tissue healing in some cases, though evidence is mixed and context-dependent. In summary, diclofenac is scientifically validated for symptomatic relief in ligament injuries, but not for direct healing of the ligament tissue itself.

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