Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Hydrolyzed beef collagen is used to support ligament repair primarily based on emerging scientific evidence, though the strength of this evidence is currently limited (rated 2/5). Collagen is a major structural protein in ligaments, and hydrolyzed collagen supplements provide bioavailable peptides that may stimulate the body's own collagen production. Some preclinical studies in animal models have demonstrated improved ligament healing and biomechanical strength following oral collagen supplementation. For example, a study in rats showed enhanced ligament repair after collagen peptide administration (Oesser et al., 2017). In humans, the majority of research has focused on joint health, tendinopathies, or skin, with only limited studies directly addressing ligament injuries. A small number of randomized controlled trials on related soft tissue injuries, such as tendinopathies and joint pain, suggest potential benefits in reducing symptoms and supporting tissue regeneration (e.g., Clark et al., 2008). However, high-quality, large-scale clinical trials specifically investigating ligament healing are lacking. Overall, while there is a plausible biological rationale and some supportive preclinical data, robust human evidence for hydrolyzed beef collagen in treating torn or injured ligaments remains limited. Its use is thus justified more by emerging science than tradition, and further research is needed to confirm its efficacy for this specific indication.

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