Evidence supporting the use of: Pomegranate
For the body system: Liver
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Pomegranate (Punica granatum) has a long history of use in traditional medicine systems, particularly in the Middle East, India, and Mediterranean regions. In Ayurvedic and Unani medicine, pomegranate has been employed for its purported liver-protective (hepatoprotective) effects, often recommended for conditions like jaundice or general liver health. This traditional use is largely based on the fruit's perceived ability to "cool" the body and support detoxification processes.
Scientific studies investigating pomegranate’s effects on liver health are limited. Some animal and in vitro studies suggest that pomegranate extracts, particularly those containing polyphenols and punicalagins, may reduce oxidative stress and inflammation in liver tissue. For example, there is preliminary evidence that pomegranate peel and juice can attenuate liver damage in animal models of chemically induced hepatotoxicity. However, there are very few well-designed human clinical trials directly assessing pomegranate’s effects on liver function or liver disease. Most available research focuses on its antioxidant properties and general health benefits rather than specific liver outcomes.
Overall, while pomegranate is used traditionally to support the liver, robust scientific validation in humans is lacking. The evidence rating is therefore low, reflecting reliance on traditional use and limited preclinical findings rather than strong clinical proof.
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