Relationship: Liver and selenium

Evidence supporting the use of: Selenium
For the body system: Liver

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Selenium is an essential trace element that plays a critical role in various biological processes, including antioxidant defense and thyroid hormone metabolism. Its relevance to liver health is primarily grounded in scientific evidence. Selenium is a component of selenoproteins such as glutathione peroxidases and thioredoxin reductases, which help protect liver cells from oxidative stress and damage caused by free radicals. Oxidative stress is a known contributor to liver diseases, including non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease, and viral hepatitis.

Several observational and experimental studies have demonstrated that selenium deficiency is associated with an increased risk of liver dysfunction and disease progression. Animal studies have shown that selenium supplementation can attenuate liver damage induced by toxins or oxidative agents. In humans, some studies suggest lower selenium levels are found in patients with chronic liver diseases compared to healthy controls. Interventional studies, though limited and sometimes small in scale, indicate that selenium supplementation may improve certain biomarkers of liver function and reduce oxidative stress in individuals with chronic liver conditions.

However, the evidence is not uniformly strong, and large-scale, high-quality randomized controlled trials are still needed to confirm the efficacy and safety of selenium supplementation for liver health in the general population. At present, selenium’s use for supporting liver function is justified by a moderate level of scientific evidence, mostly related to its role in antioxidant defense mechanisms within the liver.

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Other body systems supported by selenium

Blood
Brain
Circulatory System
Female Reproductive System
Glandular System
Hair
Heart
Immune System
Liver
Male Reproductive System
Mitochondria
Nails
Prostate
Reproductive System
Reproductive System
Skin
Testes
Testosterone
Thyroid Gland

Products containing selenium

Health Concerns

Brands

Evidence supporting the use of: Selenium
For the body system: Liver

Table of Contents

Synopsis

Other ingredients that support Liver

Other body systems supported by selenium

Products containing selenium

Health Concerns

Brands

Evidence supporting the use of: SeleniumFor the body system: Liver

Table of Contents

Synopsis

Other ingredients that support Liver

Other body systems supported by selenium

Products containing selenium

Evidence supporting the use of: Selenium
For the body system: Liver