Relationship: Liver and vitamin C

Evidence supporting the use of: Vitamin C
For the body system: Liver

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid) is an essential nutrient with well-established antioxidant properties. Its role in supporting the liver is supported by a moderate amount of scientific evidence, mostly from animal studies and limited human research. Vitamin C helps neutralize free radicals and reduce oxidative stress, processes that are particularly relevant to liver health since the liver is a primary site of detoxification and is susceptible to oxidative damage. Some studies in rodents have shown that vitamin C supplementation can protect the liver from damage induced by toxins such as alcohol, acetaminophen, and carbon tetrachloride, primarily through its antioxidant effects and by supporting the regeneration of other antioxidants like glutathione. In humans, the evidence is less robust but suggestive. Some observational studies have associated higher vitamin C intake with better markers of liver health, such as lower liver enzyme levels. There is also limited evidence indicating a potential benefit of vitamin C in nonalcoholic fatty liver disease (NAFLD) and in reducing liver inflammation. However, randomized controlled trials in humans are limited, and vitamin C is not a standard treatment for liver diseases. Therefore, while there is some scientific rationale for its supportive role, especially in the context of oxidative stress, the overall quality of evidence is moderate and does not support vitamin C as a primary therapy for liver conditions.

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Health Concerns

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Evidence supporting the use of: Vitamin C
For the body system: Liver

Table of Contents

Synopsis

Other ingredients that support Liver

Other body systems supported by vitamin C

Products containing vitamin C

Health Concerns

Brands

Evidence supporting the use of: Vitamin CFor the body system: Liver

Table of Contents

Synopsis

Other ingredients that support Liver

Other body systems supported by vitamin C

Products containing vitamin C

Evidence supporting the use of: Vitamin C
For the body system: Liver