Relationship: Liver and vitamin E

Evidence supporting the use of: Vitamin E
For the body system: Liver

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E is an antioxidant vitamin that has been studied for its potential role in supporting liver health, particularly in the context of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Several clinical trials and meta-analyses have demonstrated that vitamin E supplementation can improve liver enzyme levels and histological features in patients with NAFLD or NASH who do not have diabetes. For instance, the PIVENS trial (published in New England Journal of Medicine, 2010) reported that vitamin E (800 IU/day) improved liver histology in non-diabetic adults with NASH compared to placebo. Additionally, the American Association for the Study of Liver Diseases (AASLD) guidelines state that vitamin E may be considered as a treatment for non-diabetic adults with biopsy-proven NASH. The proposed mechanism is vitamin E’s ability to reduce oxidative stress and inflammation, both of which are implicated in liver damage progression.

However, the evidence is not universal, and vitamin E is not recommended for all liver conditions or for those with diabetes or advanced liver disease due to potential safety concerns. There is insufficient evidence to support its use for viral hepatitis or alcoholic liver disease. Overall, vitamin E’s use for liver support is backed by moderate scientific evidence in specific populations but is not broadly applicable to all liver health scenarios.

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Other body systems supported by vitamin E

Arteries
Blood
Brain
Capillaries
Circulatory System
Estrogen
Eyes
Female Reproductive System
Glandular System
Hair
Heart
Immune System
Liver
Lungs
Male Reproductive System
Mucus Membranes
Nerves
Ovaries
Reproductive System
Reproductive System
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Evidence supporting the use of: Vitamin E
For the body system: Liver

Table of Contents

Synopsis

Other ingredients that support Liver

Other body systems supported by vitamin E

Products containing vitamin E

Health Concerns

Brands

Evidence supporting the use of: Vitamin EFor the body system: Liver

Table of Contents

Synopsis

Other ingredients that support Liver

Other body systems supported by vitamin E

Products containing vitamin E

Evidence supporting the use of: Vitamin E
For the body system: Liver