Evidence supporting the use of: Astragaloside
For the health condition: Liver Detoxification

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Astragaloside, particularly Astragaloside IV, is a major active component of Astragalus membranaceus, a traditional Chinese medicinal herb. Its use for liver detoxification is grounded more in modern pharmacological research than in explicit traditional practice, although Astragalus itself has a long history in traditional medicine for supporting general vitality and immunity.

Preclinical studies (mainly in vitro and in animal models) suggest that Astragaloside IV has hepatoprotective effects. It appears to exert antioxidant activity, reduce inflammation, and inhibit liver fibrosis, all of which are relevant to liver health. Some research demonstrates that Astragaloside IV can attenuate chemically induced liver injury by modulating oxidative stress and inflammatory pathways (e.g., downregulating TNF-α, IL-6, and inhibiting TGF-β/Smad signaling).

However, the evidence remains limited to laboratory and animal studies, with a lack of robust human clinical trials specifically investigating Astragaloside IV for liver detoxification or treatment of liver diseases. Thus, while there is a scientific rationale and some early evidence for its potential benefit, the overall level of clinical evidence is low. Astragaloside is not an established therapy for liver detoxification in mainstream medicine, but ongoing research may clarify its role in the future.

More about astragaloside
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Other ingredients used for Liver Detoxification

Achyranthes
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Agrimonia pilosa
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AHCC
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astragalin
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astragalus
atractylone
aucubin
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black gram
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Products containing astragaloside

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