Evidence supporting the use of: Phospholipids (unspecified)
For the health condition: Liver Detoxification

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Phospholipids, particularly phosphatidylcholine—a major component of lecithin—have scientific evidence supporting their use in liver health and detoxification processes. Clinical and preclinical studies have shown that phospholipids can help protect liver cells (hepatocytes) from damage caused by toxins, alcohol, and medications. This protective effect is largely attributed to their role in maintaining cell membrane integrity and facilitating the repair of damaged liver cell membranes. In conditions such as non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease, and drug-induced liver injury, supplementation with phospholipids (especially essential phospholipids) has been shown to improve biochemical markers of liver function, reduce fibrosis, and enhance overall liver regeneration in some studies.

Several randomized controlled trials, mostly from Europe and Asia, report that formulations containing essential phospholipids can decrease liver enzyme levels (e.g., ALT, AST) in patients with chronic liver diseases. However, the quality and size of these studies vary, and systematic reviews have concluded that while there is modest evidence for benefit, more rigorous research is needed to confirm clinical significance. Nevertheless, current evidence supports the mechanistic rationale for phospholipids supporting liver detoxification via membrane stabilization and promoting hepatic repair processes.

In summary, there is scientific, though not definitive, evidence that phospholipids can support liver detoxification and recovery, justifying their inclusion in some liver health supplements.

More about Phospholipids (unspecified)
More about Liver Detoxification

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Products containing Phospholipids (unspecified)

We currently have no products on Vitabase that contain this ingredient.