Evidence supporting the use of: Rosmarinic acid
For the health condition: Liver Detoxification

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rosmarinic acid is a polyphenolic compound found in various herbs such as rosemary, basil, and lemon balm. Its use for liver detoxification is supported to a limited extent by preclinical scientific research, rather than by a strong tradition of use or extensive clinical evidence. In animal studies, rosmarinic acid has demonstrated hepatoprotective effects. For example, several rodent models of chemically-induced liver injury (e.g., carbon tetrachloride or acetaminophen toxicity) have shown that rosmarinic acid administration can reduce markers of liver damage, such as ALT and AST, as well as oxidative stress and inflammatory responses. The proposed mechanisms include antioxidant activity, inhibition of lipid peroxidation, and modulation of inflammatory pathways. However, the direct relevance of these findings to human liver detoxification is not firmly established. There are few, if any, rigorous clinical trials specifically evaluating rosmarinic acid for liver detoxification in humans. Therefore, while the compound has shown promise in laboratory settings, the evidence supporting its use for liver detoxification in humans remains preliminary. Most claims rely on extrapolation from basic research rather than direct demonstration of efficacy in clinical populations.

More about rosmarinic acid
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Products containing rosmarinic acid

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