Turmeric (Curcuma longa) has been used traditionally in Ayurvedic and Chinese medicine for centuries, often for its purported benefits to liver health. Modern scientific research has provided some support for its role in liver detoxification, primarily due to its active compound, curcumin. Several animal studies and limited human trials have demonstrated that curcumin possesses antioxidant, anti-inflammatory, and hepatoprotective properties. These actions may help protect the liver from damage caused by toxins, alcohol, and certain drugs.

Specifically, curcumin has been shown to modulate enzymes involved in phase I and phase II liver detoxification pathways, enhance the production of glutathione (a key antioxidant in the liver), and reduce markers of liver inflammation and oxidative stress. Clinical trials are still limited, but some small studies suggest turmeric supplementation may improve markers of liver function in patients with non-alcoholic fatty liver disease and other liver conditions. However, most of the evidence is preclinical, and higher-quality human studies are needed.

Overall, the use of turmeric for liver detoxification is supported by mechanistic studies and some early clinical data. While it is not a primary treatment for serious liver disease, turmeric may support overall liver health as part of a healthy diet and lifestyle.