Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Quercetin, a flavonoid found in many fruits and vegetables, has been studied for its potential benefits in supporting the respiratory system due to its antioxidant, anti-inflammatory, and antihistamine properties. Several preclinical studies (in vitro and animal models) suggest that quercetin can modulate inflammatory pathways relevant to lung health, such as inhibiting the release of histamine and pro-inflammatory cytokines, which are involved in allergic and asthmatic responses. Some small clinical studies have explored quercetin's effects in supporting respiratory function, particularly in allergic conditions, with mixed and generally modest results. A few trials indicate a possible reduction in upper respiratory tract infection symptoms and exercise-induced respiratory symptoms, but the evidence is not robust or consistent.

To date, there is limited high-quality clinical evidence directly supporting quercetin for general lung health or specific lung diseases such as asthma or COPD in humans. Most available human studies are small, short-term, or preliminary in nature. While the biological mechanisms are plausible and supported by laboratory research, more large-scale, rigorous clinical trials are needed to confirm efficacy and optimal dosing. Therefore, quercetin’s use to support the lung system is scientifically plausible but not yet strongly validated by clinical evidence.

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