Evidence supporting the use of: Atractylone
For the health condition: Lungs (fluid in)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Atractylone is a sesquiterpene compound found in Atractylodes species, especially Atractylodes macrocephala, a herb widely used in Traditional Chinese Medicine (TCM). In TCM, the dried rhizome of Atractylodes macrocephala (“Bai Zhu”) has been historically used to “strengthen the spleen” and “drain dampness,” which conceptually corresponds to managing excessive fluid accumulation, including in the lungs (e.g., phlegm-dampness or fluid retention syndromes). The use of Atractylone specifically for supporting or treating “fluid in the lungs” derives from this broader traditional context, where the herb is believed to help resolve internal moisture and improve the function of organs involved in fluid metabolism, such as the spleen and lungs. Modern pharmacological research on Atractylone itself is limited and mostly preclinical. Some studies indicate that extracts of Atractylodes macrocephala may have anti-inflammatory and immunomodulatory properties, but direct evidence for efficacy against pulmonary edema or fluid accumulation in the lungs is minimal. Clinical trials in humans for this specific indication are lacking. Thus, while the use of Atractylone-containing herbs to support the lungs and address fluid retention draws strong support from traditional medical practices, it is not currently validated by robust scientific studies.

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