Evidence supporting the use of: Astragalus
For the health condition: Lupus

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Astragalus (Astragalus membranaceus) is a traditional herb widely used in Chinese medicine, particularly for its reputed immune-modulating and adaptogenic properties. Its use in the context of lupus (systemic lupus erythematosus, SLE) is based primarily on traditional practices rather than robust scientific validation. In Traditional Chinese Medicine (TCM), astragalus is thought to "strengthen Qi" and support the body's defenses, and is sometimes included in formulations intended to support those with chronic illnesses, including autoimmune diseases such as lupus.

Some preliminary laboratory and animal studies suggest that astragalus may have immunomodulatory effects, potentially influencing cytokine production or protecting against kidney damage in models of autoimmune disease. However, rigorous clinical trials in humans with lupus are scarce or non-existent. Most available studies are either anecdotal, case-based, or involve animal models, making it difficult to draw firm conclusions about efficacy or safety in lupus patients. Moreover, because lupus is an autoimmune condition where the immune system attacks the body, there is theoretical concern that immune-boosting herbs like astragalus could exacerbate symptoms or trigger flares.

In summary, astragalus is used to support lupus primarily due to traditional practices and historical use in TCM, rather than strong scientific evidence. The current level of scientific support for its use in lupus is limited and rated at 2 out of 5. Anyone considering astragalus for lupus should do so with caution and consult their healthcare provider.

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