Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Cleavers (Galium aparine) has a longstanding history in traditional herbal medicine for supporting the lymphatic system, particularly in addressing swollen lymph nodes and glands. Traditional herbalists have used cleavers as a "lymphatic tonic," believing it helps stimulate lymphatic drainage, reduce fluid retention, and alleviate lymphatic congestion. Historical texts and folk remedies describe preparations of cleavers as teas, tinctures, or poultices for swollen glands, particularly in the neck and underarms. The rationale was often based on the plant's perceived "cooling" and "cleansing" properties and its ability to promote urination and detoxification.

Scientific evidence supporting these uses is limited. While some in vitro and animal studies indicate possible anti-inflammatory and diuretic effects of cleavers, high-quality human trials are lacking. There is preliminary evidence that certain compounds in cleavers—such as iridoids, flavonoids, and phenolic acids—may have mild anti-inflammatory or immunomodulatory effects, but these findings are not directly linked to lymphatic health in humans. The use of cleavers for swollen lymph nodes remains primarily rooted in traditional practice rather than robust scientific validation. As such, cleavers is often considered a low-risk herbal adjunct, but more research is needed to confirm its efficacy and mechanisms of action in lymphatic conditions.

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