Evidence supporting the use of: Goldenseal
For the health condition: Lymph Nodes or Glands (swollen)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Goldenseal (Hydrastis canadensis) has a long history of use in North American herbal medicine, especially among Native American tribes and traditional herbalists. It is most often used for its purported antimicrobial, anti-inflammatory, and immune-supporting properties. The use of goldenseal to support or treat swollen lymph nodes or glands is primarily based on traditional herbal practices rather than robust scientific evidence. Traditionally, swollen lymph nodes are interpreted as a sign of infection or inflammation, and goldenseal was employed because of its reputation as a “natural antibiotic” and immune booster. Herbalists might recommend goldenseal as a tea, tincture, or topical application in cases of swollen glands related to respiratory or throat infections.

However, scientific studies directly investigating goldenseal’s effects on lymph nodes or lymphatic tissue are lacking. Some laboratory research has demonstrated that berberine, one of goldenseal’s active alkaloids, can modulate immune responses and has antibacterial properties. Yet, these findings do not specifically validate its effectiveness for swollen glands in clinical settings. Modern herbal texts sometimes still mention goldenseal for swollen lymph nodes, but this is usually based on tradition and anecdotal reports rather than controlled research. Overall, while goldenseal is traditionally used in this context, there is minimal scientific validation for its efficacy in treating or supporting lymphatic swelling.

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