Evidence supporting the use of: AHCC
For the body system: Lymphatics

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Active Hexose Correlated Compound (AHCC) is a standardized extract derived from the mycelia of shiitake and related mushrooms. Its primary mechanism of action appears to be immunomodulation, with several studies demonstrating increased activity of natural killer (NK) cells, T cells, and dendritic cells in both animal models and some human trials. The lymphatic system, while not directly studied in most AHCC research, plays a central role in immune cell trafficking and function. Thus, AHCC is sometimes promoted for lymphatic support based on its effects on immune parameters.

However, direct scientific evidence for AHCC's effects specifically on the lymphatic system (e.g., lymph flow, lymph node health) is limited. Most research focuses on immune enhancement, particularly in the context of cancer, viral infections, and general immune status. A few small clinical studies and in vitro data suggest AHCC may enhance immune surveillance, which could indirectly support lymphatic function as part of the broader immune system.

In summary, while there is modest scientific evidence that AHCC can modulate immune responses relevant to the lymphatic system, direct evidence for its efficacy in supporting the lymphatic body system is lacking. Thus, a moderate evidence rating is appropriate, with the caveat that most findings pertain to the immune system broadly rather than the lymphatic system specifically.

More about AHCC
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Products containing AHCC

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