Evidence supporting the use of: Bacteria (unspecified)
For the body system: Lymphatics

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bacteria, specifically in the form of probiotics, have scientific validation for their role in supporting the lymphatic system, primarily via their influence on gut-associated lymphoid tissue (GALT). The GALT is a major component of the lymphatic system and accounts for a significant portion of the body’s immune cells. Numerous clinical and preclinical studies show that probiotics (such as species from the genera Lactobacillus and Bifidobacterium) can modulate immune responses, enhance the function of regulatory T cells, and promote the integrity of the gut barrier. These effects are partly mediated through interactions with dendritic cells and other immune cells residing in lymphatic tissues connected to the gut. For example, supplementation with certain probiotics has been shown to increase secretory IgA production and support mucosal immunity, which is integral to lymphatic health. While the majority of evidence focuses on immunity and gut health, the connection to the lymphatic system is well-established through its role in immune surveillance and transport. However, direct evidence regarding the effect of unspecified bacteria (not specific strains or formulations) on the lymphatic system is less robust, and effects may vary depending on the bacterial species and host factors. Therefore, the evidence supports a moderate rating, acknowledging scientific support mainly for probiotics rather than "bacteria" in general.

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