Codonopsis, often referred to as "poor man's ginseng," is a root widely used in traditional Chinese medicine (TCM). Its primary historical application has been as a general tonic, believed to strengthen the body, boost energy, and support immune function. In the context of the lymphatic system, Codonopsis is sometimes included in herbal formulas aimed at supporting immune response and enhancing the body's ability to manage fluids, though it is not directly cited as a lymphatic-specific herb in classical TCM texts. The connection to lymphatic health is generally inferential, based on its reputed immunomodulatory properties and its role in supporting "Qi" (vital energy), which is thought to underlie bodily resilience and fluid movement in TCM theory.

Scientifically, there is limited direct evidence supporting Codonopsis as a lymphatic system tonic. Some laboratory studies have shown that Codonopsis extracts may have immune-enhancing effects, such as increasing white blood cell counts or modulating cytokine production. However, these effects are general to the immune system and do not specifically target the lymphatic system. Overall, the use of Codonopsis for lymphatic support is rooted mainly in traditional herbal practices, with scientific evidence remaining preliminary and indirect.