Evidence supporting the use of: Oregon grape
For the body system: Lymphatics

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Oregon grape (Mahonia aquifolium) has a long history of use in traditional herbal medicine, particularly among Native American and European herbalists. Traditionally, the root and bark were used as a "blood purifier" and for supporting the liver, which in folk medicine was associated with promoting healthy lymphatic and immune function. The rationale was that by supporting liver detoxification and bile flow, the body's "waste removal" systems, which include the lymphatics, would also benefit. However, there is minimal direct scientific evidence specifically linking Oregon grape to improved lymphatic function. Most research and clinical interest focus on Oregon grape’s antimicrobial, anti-inflammatory, and hepatoprotective properties, largely attributed to its alkaloid content (notably berberine). Some herbalists extrapolate that these effects could indirectly support lymphatic health, as reduced inflammation and enhanced detoxification may benefit the lymphatic system. In summary, while Oregon grape is traditionally used to "support" the lymphatics, this use is based on historical application and indirect rationale rather than robust clinical research. There are no well-designed human studies directly demonstrating Oregon grape's effectiveness in supporting the lymphatic system. Its use for this purpose remains rooted in tradition and extrapolation rather than scientific validation.

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