Polyphenols are a diverse group of phytochemicals found in foods like fruits, vegetables, teas, and cocoa. Their primary health benefits are associated with antioxidant, anti-inflammatory, and vascular-protective effects. While polyphenols are not traditionally associated specifically with lymphatic health, emerging scientific evidence suggests they may have supportive effects on the lymphatic system indirectly, mainly through their impact on inflammation and vascular function.

Several experimental studies have indicated that polyphenols (such as flavonoids and resveratrol) can reduce inflammation and oxidative stress, both of which influence lymphatic vessel integrity and function. For example, some flavonoids (like diosmin and hesperidin) are used in Europe to manage chronic venous insufficiency and lymphedema, conditions that involve lymphatic congestion. Animal studies have shown that certain polyphenols can modulate lymphatic endothelial cells, promote lymphangiogenesis, and reduce tissue swelling. However, human clinical evidence specific to polyphenols and targeted lymphatic health (such as direct effects on lymph flow or lymphatic vessel repair) is quite limited.

In summary, there is some scientific basis to suggest polyphenols may support lymphatic health, but the evidence is limited and largely indirect. The use of polyphenols for lymphatic support is not as well-established as their use for cardiovascular or general anti-inflammatory purposes.