Evidence supporting the use of: Proteolytic enzyme (unspecified)
For the body system: Lymphatics

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Proteolytic enzymes, also known as proteases, are enzymes that help break down proteins into smaller peptides or amino acids. Their use to support the lymphatic system is primarily based on traditional and naturopathic practices rather than robust scientific validation. Historically, practitioners have suggested that proteolytic enzymes can "cleanse" the lymphatic system by reducing inflammation, breaking down fibrin, and supporting immune health. The rationale is that by reducing protein-based debris and inflammation in tissues, these enzymes might promote better lymphatic flow and drainage, thereby supporting detoxification and immune function.

However, while there is some scientific research on proteolytic enzymes for reducing inflammation and edema (such as in post-surgical recovery), direct evidence for their specific effects on the lymphatic system is limited. Most clinical studies focus on oral proteolytic enzyme supplements like bromelain, papain, or trypsin for indications such as reducing swelling, bruising, or pain, rather than specifically enhancing lymphatic function.

Therefore, the use of unspecified proteolytic enzymes for supporting the lymphatic system is primarily justified by tradition and anecdotal reports, rather than by high-quality scientific studies. The evidence rating is modest (2/5), reflecting the lack of direct clinical research but acknowledging a plausible rationale based on their general anti-inflammatory and tissue-modulating effects.

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