Evidence supporting the use of: Mushrooms
For the health condition: Lymphoma

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Mushrooms, particularly medicinal varieties such as Coriolus versicolor (Turkey Tail), Ganoderma lucidum (Reishi), and Lentinula edodes (Shiitake), have a long history of use in traditional medicine systems, especially in East Asia, for supporting overall immune health and as adjuncts in cancer care. This traditional use is based on the belief that certain polysaccharides and beta-glucans found in these mushrooms can modulate immune responses and potentially inhibit tumor growth.

In the context of lymphoma, the use of mushrooms is primarily traditional. While there are some preclinical studies and limited clinical trials suggesting potential immunomodulatory and anti-tumor effects of mushroom extracts, robust scientific evidence specifically supporting their efficacy in the treatment or support of lymphoma patients is lacking. For example, polysaccharide-K (PSK, from Turkey Tail) and lentinan (from Shiitake) have been studied in human cancers, with some evidence of benefit as adjuvant therapy in gastrointestinal cancers, but reliable clinical data specific to lymphoma are sparse.

Thus, while mushrooms are commonly used in traditional medicine for supporting cancer patients, the level of scientific validation for their use in lymphoma is low. They are not recognized as a standard or evidence-based therapy for lymphoma in conventional medicine. Patients should consult with their healthcare provider before using mushrooms as part of any cancer treatment regimen.

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