Relationship: Macular Degeneration and lutein

Evidence supporting the use of: Lutein
For the health condition: Macular Degeneration

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Source of validity: Scientific
Rating (out of 5): 4

Lutein is a carotenoid found naturally in the eye, especially in the macula, and is known for its antioxidant properties. Scientific evidence supports the use of lutein for the support and management of age-related macular degeneration (AMD). Multiple large-scale, randomized controlled trials, most notably the Age-Related Eye Disease Study 2 (AREDS2), have demonstrated that supplementation with lutein (often paired with zeaxanthin) can slow the progression of intermediate to advanced AMD in some individuals. The AREDS2 formula, which replaced beta-carotene with lutein and zeaxanthin, showed a modest but significant benefit in reducing the risk of advanced AMD in people at high risk. Lutein is thought to work by filtering harmful blue light and acting as an antioxidant to protect retinal cells from oxidative damage, both mechanisms relevant to the pathophysiology of AMD. While lutein supplementation does not cure AMD or restore lost vision, the evidence suggests it can help maintain visual function and slow disease progression in certain at-risk populations. Thus, current clinical guidelines often recommend lutein (as part of the AREDS2 supplement) for individuals with intermediate or advanced AMD in one eye. The body of evidence supporting its use is robust, though not absolute, and ongoing research continues to further clarify its benefits and optimal dosing.

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Other health conditions supported by lutein

Aging (prevention)
Alzheimer's Disease
Cancer (prevention)
Cataracts
Diabetic Retinopathy
Eye Problems
Eyes (spots before)
Eyesight (poor)
Free Radical Damage
Inflammation
Macular Degeneration
Memory and Brain Function

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Evidence supporting the use of: Lutein
For the health condition: Macular Degeneration

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Other ingredients used for Macular Degeneration

Other health conditions supported by lutein

Products containing lutein

Health Concerns

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Evidence supporting the use of: LuteinFor the health condition: Macular Degeneration

Table of Contents

Synopsis

Other ingredients used for Macular Degeneration

Other health conditions supported by lutein

Products containing lutein

Evidence supporting the use of: Lutein
For the health condition: Macular Degeneration