Evidence supporting the use of: Abuta
For the health condition: Malaria

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Abuta, a common name for several species in the genus Abuta (notably Abuta grandifolia and Cissampelos pareira), has a long history of use in traditional medicine in South America. Indigenous peoples have used abuta preparations for a variety of ailments, including as a treatment for fevers and malaria-like symptoms. Ethnobotanical surveys indicate that abuta roots and stems are frequently included in decoctions prescribed for febrile illnesses in the Amazon basin and other tropical regions where malaria is endemic.

However, scientific validation for abuta's antimalarial efficacy is limited. Some in vitro studies have demonstrated mild to moderate antiplasmodial activity of extracts from related Menispermaceae family plants, including Cissampelos pareira, but robust clinical studies or well-characterized active compounds directly linked to antimalarial effects in humans are lacking. Therefore, while its traditional use for malaria is well documented, the evidence from modern pharmacological research is weak or preliminary.

In summary, abuta's use for malaria is justified primarily by traditional knowledge, with little direct scientific validation to date. Its traditional use persists in some communities, but more rigorous studies are needed to confirm efficacy and safety.

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