Evidence supporting the use of: Albizia (unspecified)
For the health condition: Malaria

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Albizia species, particularly Albizia lebbeck and Albizia gummifera, have traditional uses in African and Asian ethnomedicine for treating malaria and malaria-like fevers. Ethnobotanical surveys from regions such as Nigeria, Kenya, and India document the use of Albizia bark, leaves, or root decoctions in indigenous antimalarial remedies. However, the scientific evidence is limited and preliminary. Some in vitro and animal model studies have screened extracts of Albizia species for antiplasmodial activity, with mixed or modest results. For example, a few studies have noted weak to moderate inhibitory effects against Plasmodium falciparum in laboratory settings, but these findings have not translated into strong, clinically relevant outcomes, nor have the active compounds been well-characterized for antimalarial efficacy.

Overall, the primary justification for Albizia’s use in malaria comes from traditional knowledge rather than robust scientific validation. While traditional use is well documented, and some preclinical research shows mild activity, there is a lack of high-quality clinical trials or pharmacological characterization to support its routine use as an antimalarial agent. Therefore, the evidence is best rated as modest (2/5), reflecting traditional popularity but weak scientific backing.

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