Evidence supporting the use of: Alchornea
For the health condition: Malaria

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Alchornea cordifolia, commonly known as Christmas bush, is widely used in traditional African medicine for the treatment of malaria and related febrile illnesses. Ethnobotanical surveys across West and Central Africa have documented the use of its leaves, roots, and bark as decoctions or infusions to manage malaria symptoms, including fever and chills. The plant's use is deeply rooted in local medicinal practices and is often cited by traditional healers in rural communities as a primary remedy for malaria-like symptoms.

While several in vitro and in vivo studies have investigated the plant's antiplasmodial activity, results are mixed and primarily preliminary. Some extracts of Alchornea cordifolia have shown moderate activity against Plasmodium falciparum in laboratory settings, but these effects are generally less potent than standard antimalarial drugs. The mechanisms are not fully understood, and active compounds have not been definitively isolated or characterized for clinical efficacy. To date, there are no high-quality clinical trials supporting its effectiveness in humans for malaria treatment.

In summary, the use of Alchornea cordifolia for malaria is primarily supported by traditional knowledge, with limited and inconclusive scientific validation. Further research is required to determine its true efficacy and safety profile in the treatment of malaria.

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