Evidence supporting the use of: Blepharis
For the health condition: Malaria

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Blepharis species, particularly Blepharis edulis and Blepharis linariifolia, have traditional uses in African and some Asian ethnomedicine, including as supportive remedies for malaria and febrile illnesses. Ethnobotanical surveys document that local healers in regions such as Sudan, Nigeria, and Ethiopia use extracts or decoctions of Blepharis leaves or seeds as part of antimalarial herbal mixtures or as a standalone remedy to reduce fever and alleviate symptoms associated with malaria. The rationale for its use is primarily grounded in traditional knowledge and long-standing cultural practices.

However, there is limited direct scientific research validating Blepharis’s efficacy against malaria parasites. A few in vitro and in vivo studies have examined extracts from related species for general antimicrobial or anti-inflammatory effects, but robust evidence specifically demonstrating antiplasmodial activity is lacking. As a result, the support for Blepharis in malaria treatment remains mainly based on ethnomedical tradition rather than rigorous clinical or pharmacological validation.

In summary, Blepharis’s use for malaria is rooted in tradition, with only modest preliminary scientific exploration and no high-quality evidence confirming its effectiveness. Its role in malaria management should be understood as supportive in traditional settings, not as a replacement for proven antimalarial therapies.

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