Evidence supporting the use of: Clerodendrum phlomidis
For the health condition: Malaria

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Clerodendrum phlomidis is used in traditional medicine systems such as Ayurveda and Siddha to treat a variety of ailments, including fever and conditions associated with fever, like malaria. Ethnobotanical surveys and historical texts document its use for intermittent fevers, which are characteristic of malaria. The plant’s leaves, roots, and extracts have been employed by traditional healers for this purpose in parts of India and Sri Lanka.

Scientific validation for its anti-malarial efficacy remains limited. Some preliminary in vitro and in vivo studies have assessed the anti-plasmodial activity of Clerodendrum phlomidis extracts. For instance, a few studies have demonstrated modest inhibitory effects of plant extracts against Plasmodium falciparum in laboratory settings, but these findings are not yet robust or replicated widely. No large-scale clinical trials or strong pharmacological evidence currently support the use of this plant as a reliable anti-malarial agent.

In summary, the use of Clerodendrum phlomidis for malaria is primarily justified by traditional use, with only low-level scientific evidence supporting any anti-malarial activity. Its role continues to be mainly ethnomedical, and more rigorous scientific investigation is required to validate its efficacy and safety for malaria treatment.

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