Evidence supporting the use of: Lophira lanceolata
For the health condition: Malaria

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Lophira lanceolata, commonly known as "false shea" or "ironwood," has a longstanding history of use in traditional African medicine. Its bark, leaves, and seeds are employed by various communities, particularly in West and Central Africa, for the treatment of malaria and related febrile illnesses. Ethnobotanical surveys consistently report the use of Lophira lanceolata decoctions or infusions as antimalarial remedies. However, the scientific evidence supporting its efficacy is limited. Some in vitro studies have screened extracts from Lophira lanceolata for antiplasmodial activity, with a few suggesting modest inhibitory effects against Plasmodium falciparum, the parasite responsible for the most severe form of malaria. These results, however, are preliminary and lack robust clinical validation. No high-quality human clinical trials have been conducted to confirm its safety or effectiveness for malaria treatment. Thus, while its use is well established in traditional medicine, current scientific evidence is insufficient to firmly support or refute its efficacy for malaria, and it should not substitute for proven antimalarial drugs.

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