Evidence supporting the use of: Oldenlandia diffusa
For the health condition: Malaria

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Oldenlandia diffusa, also known as Hedyotis diffusa, is primarily used in traditional medicine for a variety of ailments, including as a supportive treatment for malaria. In the context of malaria, its use is documented in traditional Chinese medicine and some ethnobotanical sources from South and Southeast Asia. These traditional practices often employ decoctions or extracts of the plant, sometimes in combination with other herbs, to alleviate fever and symptoms associated with malaria.

However, scientific evidence supporting its efficacy against malaria is limited. A few in vitro studies have explored the antiplasmodial activity of Oldenlandia diffusa extracts, but results are generally weak or inconclusive. The majority of research on Oldenlandia diffusa focuses on its anti-inflammatory, anticancer, and antimicrobial properties rather than direct antimalarial effects. No high-quality clinical trials or robust preclinical studies definitively support its use as an antimalarial agent.

In summary, the use of Oldenlandia diffusa for malaria is primarily justified by traditional practices rather than strong scientific validation. Its role in malaria management in traditional medicine is noted, but current evidence does not support it as an effective or reliable antimalarial therapy.

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