Evidence supporting the use of: Phyllanthus fraternus
For the health condition: Malaria

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Phyllanthus fraternus, a plant in the Phyllanthaceae family, has a history of use in traditional medicine systems, particularly in South Asia. In ethnobotanical surveys, the whole plant or its extracts have been reported as being used by traditional healers to manage symptoms of malaria, such as fever, chills, and malaise. The justification for its use is primarily based on traditional practices rather than rigorous scientific validation. Some in vitro studies have indicated weak antiplasmodial activity of Phyllanthus species extracts, but these findings are preliminary and often not specific to P. fraternus. There is a lack of comprehensive clinical trials or robust pharmacological studies establishing efficacy or safety for malaria treatment in humans. The plant does contain bioactive compounds such as lignans, flavonoids, and tannins, which may provide some rationale for its use. However, the available evidence does not support its use as a standalone or primary therapy for malaria. It is important to note that while P. fraternus may play a supportive role in traditional contexts, it should not replace evidence-based antimalarial treatments. In summary, its use for malaria is supported by traditional knowledge, but scientific evidence remains limited and inconclusive.

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