Evidence supporting the use of: Arginine
For the body system: Male Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Arginine, also known as L-arginine, is an amino acid that plays several roles in the body, including as a precursor to nitric oxide, a compound that helps dilate blood vessels and improve blood flow. The use of arginine to support the male reproductive system, particularly in the context of erectile function and fertility, has some scientific basis. Several studies have shown that arginine supplementation can improve erectile function in men with mild to moderate erectile dysfunction, likely due to its role in enhancing nitric oxide-mediated vasodilation.

Meta-analyses and clinical trials have reported moderate improvements in erectile function scores compared to placebo. There is also limited evidence suggesting that arginine may improve sperm motility and count in some cases of male infertility, although the quality and size of these studies vary and further research is needed to confirm these findings. Overall, while not universally effective for all men or conditions, the use of arginine for supporting aspects of male reproductive health is supported by a moderate level of scientific evidence, particularly in the context of vascular-related erectile dysfunction.

It is important to note that most studies highlight that the effects are modest and may be enhanced when arginine is combined with other supplements such as pycnogenol. The safety profile of arginine is generally favorable at typical supplemental doses, but individuals with certain health conditions should consult a healthcare provider before use.

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