Evidence supporting the use of: Barrenwort
For the body system: Male Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Barrenwort (Epimedium species), also known as horny goat weed, has a long history of traditional use in Chinese medicine for enhancing male sexual health and vitality. Its primary bioactive compound, icariin, has been the focus of several scientific studies. Animal studies and some in vitro research suggest that icariin may have a mild PDE5 inhibitory effect—similar in mechanism, though much weaker, to drugs like sildenafil (Viagra). This could theoretically help support erectile function by increasing blood flow to the penis. Some studies also indicate that icariin may modulate nitric oxide production and support testosterone synthesis, both of which are relevant to male reproductive health. However, robust clinical evidence in humans is limited. Most human studies are small, lack rigorous controls, or are preliminary in nature. There are anecdotal and traditional reports of improved libido and erectile function, but few high-quality randomized controlled trials have been published. Therefore, while there is some scientific rationale and early evidence supporting the use of barrenwort for male reproductive health, its efficacy is not well established, and more research is needed to confirm these effects in humans. At present, the evidence base is best described as weak but plausible, justifying a moderate-low rating.

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