Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Fatty acid or fat/oil supplements, such as omega-3 and omega-6 polyunsaturated fatty acids, have a moderate level of scientific support for their role in supporting the male reproductive system, particularly in regard to sperm health and testosterone production. Multiple studies have shown that omega-3 fatty acids (notably EPA and DHA, found in fish oil) are incorporated into sperm cell membranes, enhancing fluidity and improving sperm motility and morphology. A meta-analysis published in "Andrology" (2020) found that supplementation with omega-3 fatty acids was associated with improvements in total sperm count, concentration, motility, and morphology in infertile men.

Furthermore, animal studies and some human research suggest that fatty acids may influence testosterone synthesis by affecting Leydig cell function in the testes. However, while improvements in certain semen parameters have been observed, evidence linking fatty acid supplementation to increased pregnancy rates or substantial improvements in overall male fertility outcomes remains limited. The mechanisms are believed to be related to anti-inflammatory effects, antioxidant actions, and improvements in cell membrane composition.

Overall, while the evidence is not definitive and high-quality clinical trials are still needed, there is a reasonable scientific basis for the use of fatty acid supplements to support certain aspects of male reproductive health, especially regarding sperm quality. Therefore, the justification for use is primarily scientific, with a moderate level of supporting evidence.

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