Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Diindolylmethane (DIM) is a compound formed during the digestion of indole-3-carbinol, which is found in cruciferous vegetables like broccoli and Brussels sprouts. Its use for supporting the male reproductive system is based primarily on its effects on estrogen metabolism. Scientifically, DIM has been shown in cell and animal studies to promote the breakdown of estradiol into less potent estrogen metabolites and to modulate the ratio of estrogen to testosterone. This has led to interest in DIM as a supplement for men, particularly those concerned with estrogen dominance, prostate health, or hormonal balance.

However, the evidence in humans is limited. A few small clinical trials and case reports suggest that DIM may influence estrogen metabolism and possibly have a role in benign prostate hyperplasia (BPH) or prostate cancer prevention, but robust, large-scale studies are lacking. There is some preliminary evidence that DIM might reduce the risk of prostate cancer or help with prostate health by modulating hormone activity, but these findings are not conclusive.

Overall, while there is some scientific rationale and early evidence supporting the use of DIM for male reproductive health, the clinical evidence is not strong enough to warrant a high rating. Most claims are extrapolated from animal models or mechanistic studies rather than definitive clinical outcomes in men.

More about DIM (diindolylmethane)
More about Male Reproductive System

Other ingredients that support Male Reproductive System

Other body systems supported by DIM (diindolylmethane)

Products containing DIM (diindolylmethane)

Pure Encapsulations DIM Detox
Douglas Laboratories DIM ® Enhanced
Douglas Laboratories DIM ® Enhanced
Designs For Health DIM-Evail™
Pure Encapsulations DIM-PRO® 100
Pure Encapsulations DIM-PRO® 100
Metagenics EstroFactors®
Designs For Health FemGuard+Balance™
Thorne Hormone Advantage DIM Advantage
Integrative Therapeutics Indolplex
Designs For Health LibidoStim-M™
Designs For Health Prostate Supreme™
Designs For Health Prostate Supreme™
Pure Encapsulations PureGenomics® UltraMultivitamin
Pure Encapsulations UltraDetox 10-Day Pure Pack