Evidence supporting the use of: L-arginine
For the body system: Male Reproductive System

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

L-arginine is an amino acid that serves as a precursor to nitric oxide, a compound that relaxes blood vessels and improves blood flow. Its use to support the male reproductive system, particularly for erectile function, has a scientific basis. Several clinical studies have investigated L-arginine supplementation for erectile dysfunction (ED), a key aspect of male reproductive health. Some double-blind, placebo-controlled trials have shown that L-arginine (typically at doses of 2-5 grams daily) can improve erectile function in men with mild to moderate ED, likely by enhancing nitric oxide-mediated vasodilation in penile tissue. Meta-analyses suggest a modest benefit, especially when combined with other agents like pycnogenol; however, results are mixed, and not all studies show significant improvement.

There is less direct evidence supporting L-arginine for other aspects of male reproductive health, such as fertility or testosterone production, though some small studies have suggested potential benefits for sperm motility and count. Overall, the scientific evidence is moderate (rated 3/5), with reasonable mechanistic plausibility and clinical trial support for erectile function, but less robust or consistent data for broader reproductive health effects.

L-arginine is generally considered safe at recommended doses, though it may interact with certain medications (e.g., nitrates). More large-scale, well-controlled studies are needed to fully establish its efficacy and optimal use in supporting the male reproductive system.

More about L-arginine
More about Male Reproductive System

Other ingredients that support Male Reproductive System

amino acids
ashwagandha
aspartic acid
beta-sitosterol
sesame
boron
broccoli
caterpillar mushroom
cordyceps
cowage seed
d-alpha tocopherol
damiana
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
fenugreek
folate
ginseng
gokhru
L-arginine
L-citrulline
lycopene
maca
magnesium
Melatonin
Muira puama
Nettle
parsley
pomegranate
protein
pumpkin
pygeum
rehmannia glutinosa
saffron
saw palmetto
selenium
black ginger
Tongkat ali
tribulus
velvet bean
vitamin B
vitamin D
vitamin E
Zinc
suma
anise
smilax
Caesalpinia crista
lingzhi
cistanche
dodder
royal jelly
equol (proprietary)
trace minerals
barrenwort
wheat germ
herbal blend (proprietary)
Yohimbe
antler
Angelica
Alchornea
avocado
Abuta
Allium tuberosum
anti-aromatase
animal protein
black seed
Butea monosperma
black galingale
Beef liver
Bulbine natalensis
Brazil nut
ba ji tian
Butea superba
bee products
Borassus aethiopum
Curculigo orchioides
Chinese mountain ant
Cucurbita
Cnidium
Clerodendrum phlomidis
Cynomorium
Chinese fleeceflower
Chinese pond turtle
Chlorophytum
cruciferous
Cyanotis vaga
catuaba
Crinum latifolium
Cyanotis arachnoides
DHEA
D-Aspartic Acid
deer velvet
date
eurycomanone
egg
Euryale seed
elk antler
Eurycoma Longifolia
folic acid
fo-ti
furostanols
fish
fatty acids
Fadogia agrestis
Ginsenosides
garden cress
Hygrophila
horny goat weed
Indian sarsparilla
icariin
Jatropha macrantha
Kigelia africana
Kokilaksha
Leptadenia
Loranthus
lipids
macamides
maral root
Massularia acuminata
Montanoa tomentosa
macaenes
Nigella seed
Nymphaea caerulea
Orchis latifolia
Osthole
Protodioscin
Pedalium
Rehmannia
Rhaponticum
Selenocysteine
Selenomethionine
Safed musli
Semecarpus anacardium
Shataverins
Shilajit
Trichilia catigua
Tribuloside
Tiger Nut
Tribulus Terrestris
Withanolides
Walnut
Yohimbine

Products containing L-arginine

Designs For Health Amino Acid Supreme™
Designs For Health Amino Acid Synergy
Pure Encapsulations Amino-NR
Pure Encapsulations Amino Replete
Metagenics ArginCor®
Metagenics Arginine Plus™
Metagenics BioPure Protein® Powder
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Douglas Laboratories Cysto Renew ®
Douglas Laboratories Free Form Amino
Pure Encapsulations Growth Hormone Support
Vitabase HGH Complex
Klean Athlete Klean Isolate ™
Pure Encapsulations l-Arginine
Pure Encapsulations l-Arginine
Designs For Health L-Arginine
Douglas Laboratories L-Arginine 500 mg
Douglas Laboratories L-Arginine 700 mg
Thorne L-Arginine Plus Perfusia Plus
Thorne L-Arginine Sustained Release Perfusia-SR
Pure Encapsulations Nitric Oxide Support
Designs For Health NOx Synergy™
Metagenics Perfect Protein® Pea & Rice Chocolate Powder
Metagenics Perfect Protein Pea & Rice Vanilla Powder
Metagenics Perfect Protein Whey Chocolate
Metagenics Perfect Protein Whey Vanilla
Metagenics Ultra Glucose Control® Chocolate
Metagenics Ultra Glucose Control Chocolate
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Glucose Control Vanilla
Metagenics UltraClear RENEW Detox Powder Berry
Metagenics UltraClear RENEW Detox Powder Chai
Metagenics UltraClear RENEW Detox Powder Vanilla
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraMeal Advanced Protein® Dutch Chocolate
Metagenics UltraMeal Advanced Protein French Vanilla
Metagenics UltraMeal Advanced Protein Plain
Metagenics UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics UltraMeal Cardio 360° Pea/Rice Vanilla