Evidence supporting the use of: Macamides
For the body system: Male Reproductive System

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Macamides are bioactive compounds found in maca (Lepidium meyenii), a plant native to the Andes of Peru. The use of maca root, and by extension macamides, to support male reproductive health is primarily rooted in traditional medicine. Indigenous peoples of the Andes have consumed maca for centuries, attributing to it properties that enhance fertility, libido, and stamina, especially in men. Several ethnobotanical studies document these traditional uses.

Modern scientific research on macamides specifically is still emerging. Some animal studies and limited human clinical trials on maca root (not isolated macamides) suggest potential benefits for sperm quality, libido, and mild improvements in sexual desire. However, the evidence is not robust or conclusive, and the specific role of macamides, as opposed to other constituents of maca, remains to be fully elucidated. No large-scale, well-controlled human trials have definitively proven macamides’ efficacy for male reproductive health. Overall, the evidence supporting macamides for this purpose is based more on traditional use and preliminary research, rather than strong scientific validation.

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Products containing Macamides

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